Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs [Format Kindle] Author: Tim Kirkham Steven J Cooper | Language: English | ISBN:
B001936CYA | Format: PDF, EPUB
Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs Free download Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs from with Mediafire Link Download Link
Présentation de l'éditeur
There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems.
Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication.
* Provides an integrative view of the many systems involved in appetite how they interact to effect food intake (i.e. the brain, endocrine, gut, liver etc.)
* Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts
* Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds
Books with free ebook downloads available Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs
The subject is timely, the title is promising but this book is one of the examples where you ask for whom it has been written? If you know the subject, you do not need this book, the many excellent reviews in scientific journals suffice. Despite many agreeable chapters, if you do not know the subject you end up with more confusion than clarity (if you managed to get beyond chapter 1). What is lacking is not the expertise of the authors but a meaningful integration of the different chapters. Moreover, there is a screaming absence of illustrations (an almost insulting lack for those who wish to learn). How can one appreciate this subject without having a single chapter that tries to explain, by means of rich illustrations, the neural circuits involved in regulation of appetite? A few fold-outs perhaps that aim to connect the different subjects into "an integrative system". With all respect to the authors and editors, this book can and should be improved. If one truly has the reader in mind, a real and much appreciated "integrative" approach to appetite control may emerge.
Par cell biology promotion
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